Ups and downs of optokinetic nystagmus

Study of congenital nystagmus: optokinetic nystagmus.

A severe defect of optokinetic nystagmus (OKN) was found in 46 patients with congenital nystagmus. Abnormal patterns of OKN, such as superimposition of pendular oscillations on the optokinetic slow component and inversion of OKN, were observed. Optokinetic gain (eye movement velocity/drum velocity) was decreased compared to that in normal subjects, and optokinetic after-nystagmus, or transient ...

Mdm2: the ups and downs.

Mdm2 was first described 12 years ago. Interest in this oncogene has risen since its identification as a protein that binds and efficiently inactivates the p53 tumor suppressor protein. This interest was further boosted by the discovery that the mdm2 gene is actually a target for direct transcriptional activation by p53, thus defining an autoregulatory feedback loop for the intracellular modula...

Scotopic Optokinetic Nystagmus Thresholds

Although it is now well established that a variety of ocular and systemic diseases, including diabetes, are harmful to the SWS cone pathway, causing a decrease in SW sensitivity,"the site(s) of the loss is not well known. The loss in SW sensitivity in diabetes has been variously attributed to changes in the lens, loss of SWS cone receptors due to their greater vulnerability to insult, the reduc...

TRANSSENTENTIAL MEDITATIONS Ups and downs in dynamic semantics TRANSSENTENTIAL MEDITATIONS Ups and downs in dynamic semantics

Vertical optokinetic nystagmus and optokinetic afternystagmus in humans.

Vertical optokinetic nystagmus (OKN) and optokinetic afternystagmus (OKAN) were recorded in 6 normal subjects using the magnetic scleral search coil technique in order to reevaluate the up-down symmetry of these responses. The effects of body position relative to gravity were investigated by comparing OKN and OKAN elicited with the subjects in an erect and in a lateral side position. No consist...